Mining as an extractive activity has the potential to promote sustainable economic growth in developing countries; however this largely depends on how the activities are regulated.Mining contributes to environmental pollution and degradation, and the social degeneration of local communities.Corporate social responsibility initiatives are often self
Characterization of two candidate genes, NCoA3 and IRF8, potentially involved in the control of HIV-1 latency
Abstract Background The persistence of latent HIV-1 reservoirs is the principal barrier preventing the eradication of HIV-1 infection in patients by current antiretroviral therapy.It is thus crucial to understand the molecular mechanisms involved in the establishment, maintenance and reactivation of HIV-1 latency.Since chromatin remodeling has been
Interpreting COVID-19 and Virtual Care Trends: Cohort Study
BackgroundThe coronavirus disease (COVID-19) pandemic is rapidly spreading across the world.As of March 26, 2020, there are more than 500,000 cases and more than 25,000 deaths related to COVID-19, and the numbers are increasing by the hour.ObjectiveThe aim of this study was to explore the trends in confirmed COVID-19 cases in North Carolina, and to
A Two-Step Estimation Method for a Time-Varying INAR Model
This paper proposes a new time-varying integer-valued autoregressive (TV-INAR) model with a state vector following a logistic regression structure.Since the autoregressive coefficient in the model is Undercounter Freezers time-dependent, the Kalman-smoothed method is applicable.Some statistical properties of the model are established.To estimate th